A case of lymphocytic hypophysitis presenting as a pituitary macroadenoma.
نویسندگان
چکیده
The results of her basal pituitary function tests taken at that time are tabulated below ( table 1 ). These results suggest adrenocorticotropic hormone (ACTH), thyroid stimulating hormone (TSH) and prolactin deficiencies. A repeat MRI scan of her pituitary demonstrated a normal pituitary gland with no optic chiasmal compression, nor evidence of pituitary haemorrhage. In view of the spontaneous resolution of her visual field defect and pituitary macroadenoma, together with the ACTH and TSH deficiencies, a clinical diagnosis of lymphocytic hypophysitis was made. The patient was treated with hydrocortisone and thyroxine. On further follow-up, she remains well with no headaches or visual disturbances, a normal menstrual cycle and improved energy levels.
منابع مشابه
Spontaneous regression of one nonfunctioning pituitary macroadenoma associated with abnormal liver enzyme tests
Background: Nowadays, drug and observation are advised to patients with lymphocytic hypophysitis and in some cases with nonfunctioning pituitary macoadenoma, instead of surgery. Case presentation: In this article, we report a woman with nonfunctional pituitary macroadenoma and panhypopitutarism and negative criteria for lymphocytic hypophysitis associated with increased liver enzymes. After thr...
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Lymphocytic hypophysitis is an uncommon disease with a variable presentation and unclear pathophysiology. We present the case of a 30 year old woman who presented with features typical of a pituitary macroadenoma. She underwent a transphenoidal resection of the mass and histopathological examination revealed lymphocytic hypophysitis. This case illustrates the difficulty in differentiating pitui...
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Among pituitary disorders having mass effect of the pituitary gland, nonfunctioning pituitary macroadenoma and lymphocytic hypophysitis are difficult to differentiate without histological examination. In order to efficiently distinguish lymphocytic hypophysitis and pituitary tumors, we studied the presence of autoantibodies against prohormone-processing enzymes, prohormone convertase (PC) 1/3, ...
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Lymphocytic hypophysitis is a rare inflammatory disease of the pituitary gland that is being increasingly recognized as a cause of hypopituitarism. This condition may be due to an autoimmune pituitary destruction which usually occurs in young women during pregnancy or in the immediate postpartum period. We describe a case of cystic pituitary mass in a thirty-eight year-old woman presenting with...
متن کاملDetection of autoantibodies against the pituitary-specific proteins in patients with lymphocytic hypophysitis.
OBJECTIVE Several reports have described antipituitary antibodies by immunofluorescent or immunoblotting methods in patients with lymphocytic hypophysitis. However, with the exception of the pituitary hormones, individual antigens specific for the pituitary gland have not been studied. To understand the pathogenesis of lymphocytic hypophysitis and to diagnose this disease efficiently, we studie...
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ورودعنوان ژورنال:
- Hormone research
دوره 68 Suppl 5 شماره
صفحات -
تاریخ انتشار 2007